MicroRNA-155 modulates methotrexate-induced spatial memory impairment by disruption of the blood-brain barrier integrity
IP MTX can induce significant cognitive impairment, which is related to the disruption of BBB integrity. miR-155 plays a vital role in the regulation of MTX-induced cognitive impairment, mainly through the maintenance of BBB integrity.
Authors
- Li‐Tung Huang (ORCID: https://orcid.org/0000-0001-7403-288X)
- Hong‐Ren Yu (ORCID: https://orcid.org/0000-0003-1242-8760)
- Jiunn‐Ming Sheen (ORCID: https://orcid.org/0000-0002-1581-0052)
- Yu-Chieh Chen (ORCID: https://orcid.org/0000-0002-1838-276X)
Institutions
- Chang Gung University (TW)
- Kaohsiung Chang Gung Memorial Hospital (TW)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111240
- Citations
- 2
- Primary Topic
- Cancer-related cognitive impairment studies
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- Kaohsiung Chang Gung Memorial Hospital