Growth factors IGF-1 and KGF and adipose-derived stem cells promote migration and viability of primary human keratinocytes in an in vitro wound model
This study provides potential for the improvement of epidermal transplantation in the treatment of chronic wounds using xenogen-free isolated and cultivated keratinocytes, growth factors, and ADSC. Translating these results into clinical application may help accelerate wound healing and shorten the time until patients can return to everyday life.
Authors
- Rafael Schmid (ORCID: https://orcid.org/0000-0002-4508-9243)
- Annika Kengelbach‐Weigand (ORCID: https://orcid.org/0000-0003-0583-1412)
- Ajay Peddi
- Theresa Promny (ORCID: https://orcid.org/0000-0003-1894-9030)
- Anja Miriam Boos (ORCID: https://orcid.org/0000-0003-2533-5563)
- Raymund E. Horch (ORCID: https://orcid.org/0000-0002-6561-2353)
- Nina Stadelmann
- David Ostendorf
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-02-06
- DOI
- https://doi.org/10.3389/fmed.2025.1516116
- Citations
- 7
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.18
Funders
- George Washington University
- Deutsche Forschungsgemeinschaft
- Kinetic Concepts