Role of microvascular pericyte dysfunction in antibody-mediated rejection following kidney transplantation
ABMR episodes worsened the long-term prognosis of transplanted kidneys. pericyte dysfunction appears to be one of the crucial causes of poor prognosis in ABMR patients. <i>In vitro</i> studies demonstrated that dysfunction of microvascular pericytes can result in damage to vascular endothelial cells, with autophagy impairment being a significant mechanism contributing to pericyte dysfunction.
Authors
- Fei Shuang (ORCID: https://orcid.org/0000-0001-6333-9237)
- Jie Xu (ORCID: https://orcid.org/0000-0002-9321-9671)
- Juan Pu (ORCID: https://orcid.org/0000-0002-3278-2591)
- Hao Chen (ORCID: https://orcid.org/0000-0002-6282-0237)
- Zhijian Han
- Li Sun
- Xiaobing Ju
- Min Gu (ORCID: https://orcid.org/0000-0002-4670-9109)
- Jun Tao
- Ruoyun Tan
- Zijie Wang (ORCID: https://orcid.org/0000-0002-0148-5244)
Institutions
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1080/0886022x.2025.2458749
- Citations
- 5
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 9.93
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province