A rapid method for the preparation of an in vitro osteoporosis model of calf vertebrae: histological and biomechanical study
The data from this study indicate that the decalcification method is effective and capable of rapidly establishing an osteoporotic model suitable for biomechanical testing of clinical devices. This method offers the benefits of ease of operation, reliability, and a controllable degree of osteoporosis.
Authors
- Qiang Ma (ORCID: https://orcid.org/0000-0001-7635-2342)
- Anli Shi (ORCID: https://orcid.org/0009-0000-4081-5560)
- Jintu Fan (ORCID: https://orcid.org/0000-0002-7130-0081)
- Zhaohui Ge (ORCID: https://orcid.org/0000-0001-5167-4601)
- Jiaxin Li (ORCID: https://orcid.org/0000-0002-1681-3271)
- Yijie Liu (ORCID: https://orcid.org/0000-0002-5961-0546)
Institutions
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-02-05
- DOI
- https://doi.org/10.3389/fbioe.2025.1527800
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00