Intervening Non-Small-Cell Lung Cancer Progression by Cell Membrane Coated Platycodin D via Regulating Hsa-miR-1246/FUT9/GSK3β Pathway
The application of PD prompted an increase in the expression levels of hsa-miR-1246 and a concurrent decrease in FUT9. Importantly, the therapeutic efficacy of PD in vivo was markedly enhanced through homologous cell delivery system. Collectively, this study revealed the potential utility of PD in the treatment of NSCLC progression.
Authors
- Yanlin Xin
- Yuanyuan Guo (ORCID: https://orcid.org/0000-0002-4571-9938)
- Shuyu Zheng (ORCID: https://orcid.org/0000-0003-3114-8705)
- Tianming Lu (ORCID: https://orcid.org/0000-0003-3103-6973)
- Ziao Zhou
- Zejuan Xie (ORCID: https://orcid.org/0000-0003-2051-3930)
- Ruogu Qi (ORCID: https://orcid.org/0000-0001-9222-9272)
- Keyu Cheng (ORCID: https://orcid.org/0000-0002-1527-9361)
- Shanshan Wang (ORCID: https://orcid.org/0000-0002-6651-2821)
- Jiamin Lin
Institutions
- Nanjing University of Chinese Medicine (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/ijn.s479675
- Citations
- 4
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.22