Genomic characteristics of ST6115 carbapenem-resistant Klebsiella pneumoniae coharboring blaNDM-1 and blaIMP-4
We report a clinical ST6115 strain HD8428 and identify the coexistence of <i>bla</i> <sub>NDM-1</sub> and <i>bla</i> <sub>IMP-4</sub> in the IncHI5 type plasmid pHD8428-NDM-IMP. HD8428 was resistant to a wide range of antibiotics and harbored the transmissible plasmid pHD8428-NDM-IMP, which made it a potential threat to public health. Our study indicates that the healthcare system and services should remain vigilant regarding the spread and prevalence of ST6115.
Authors
- Feinan Qian (ORCID: https://orcid.org/0000-0002-4316-115X)
- Hong Du (ORCID: https://orcid.org/0000-0001-6652-4702)
- Zhichen Zhu (ORCID: https://orcid.org/0000-0002-3144-4611)
- Jie Zhu (ORCID: https://orcid.org/0000-0002-1879-983X)
- Yaxuan Zhai
- Qizhao Gao (ORCID: https://orcid.org/0000-0002-0363-3001)
- Xiaofang Xie (ORCID: https://orcid.org/0000-0003-3010-8349)
Institutions
- Soochow University (CN)
- Central People's Hospital of Zhanjiang (CN)
- Second Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-02-05
- DOI
- https://doi.org/10.3389/fmicb.2025.1545161
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.59
Funders
- Ministry of Education, India
- Soochow University