Liposomal amphotericin-B-induced atrial fibrillation with hypomagnesaemia in acute invasive mucormycosis of the right maxillary sinus

Liposomal amphotericin B (LAmB) is the preferred drug for treating mucormycosis, a dangerous opportunistic infection caused by fungal pathogens. This case report details the medical history and treatment of a female patient who had type 2 diabetes, pulmonary artery hypertension and congenital heart disease. She was diagnosed with acute invasive mucormycosis in her right maxillary sinuses and underwent right endoscopic debridement. Throughout her treatment, she received 50 mg of injection LAmB. However, her magnesium levels decreased, and on the 10 th day of treatment, she developed abnormal heart rhythms, specifically atrial flutter. This condition was successfully managed with an injection of digoxin (0.25 mg). Thus, continuous monitoring of magnesium and potassium levels, as well as electrocardiogram monitoring, is crucial in these cases. Failure to correct low potassium and magnesium levels in patients with congenital heart disease may result in heart rhythm disturbances or artery spasms. In our case, they treated it with syrup potassium chloride, and an injection of magnesium was given as a stat doses. Careful management and close monitoring are required to treat some cardiac-related effects of drugs and to achieve optimal outcomes in complex cases of mucormycosis treated with LAmB in our case continuous monitoring helped us with the achievement of treatment.