Analysis of the correlation between the dose exposure intensity and apatinib in advanced gastric cancer: a retrospective cohort study
The efficacy of apatinib in advanced gastric cancer was significantly positively correlated with dose exposure intensity, and HDEI can prolong PFS and OS. Early application of low-dose apatinib (250 mg/d) can improve patients' tolerability, and the adverse reactions are controllable.
Authors
- Catharina Jialing Tao
- Lan Gao
- Xiao Ma (ORCID: https://orcid.org/0000-0001-9940-8468)
- Shunan Che
Institutions
- Capital Medical University (CN)
- Kunming Medical University (CN)
- Beijing Friendship Hospital (CN)
- The First People's Hospital of Zhaoqing (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-02-05
- DOI
- https://doi.org/10.3389/fonc.2025.1470462
- Citations
- 1
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.52