Icariin improves erectile function in spontaneously hypertensive rats by downregulating GRK2 in penile cavernous tissue
Icariin downregulates the expression of GRK2 in the penile cavernous tissue of SHRs, upregulates the AKT/eNOS/NO pathway, decreases oxidative stress and apoptosis, and ultimately improves erectile function.
Authors
- Rui Jiang (ORCID: https://orcid.org/0000-0003-1849-3643)
- Yanke Li (ORCID: https://orcid.org/0009-0009-3176-0188)
- Jun Jiang (ORCID: https://orcid.org/0000-0003-1292-7236)
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- The Journal of Sexual Medicine
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1093/jsxmed/qdaf014
- Citations
- 2
- Primary Topic
- Medicinal Plant Pharmacodynamics Research
- Type
- article
- Field-Weighted Citation Impact
- 3.11