Sex-specific associations between estimated glucose disposal rate and cognitive decline in middle-aged and older adults in China: a longitudinal cohort study
Higher eGDR was significantly associated with slower cognitive decline, particularly among women. These findings underscore the potential of eGDR as a marker for identifying and mitigating cognitive decline and highlight the importance of sex-specific strategies to address insulin resistance and promote cognitive health.
Authors
- Hao Wu (ORCID: https://orcid.org/0000-0003-1915-7684)
- Chun Luo (ORCID: https://orcid.org/0000-0003-1253-5187)
- Bingyang Liu (ORCID: https://orcid.org/0000-0001-8479-778X)
- Xiaoying Shen (ORCID: https://orcid.org/0000-0002-0618-0423)
- Jianqing Zhou (ORCID: https://orcid.org/0000-0001-8039-6188)
- Shuang Han (ORCID: https://orcid.org/0000-0001-9736-0093)
Institutions
- Ningbo University (CN)
- Westlake University (CN)
- Ningbo Medical Center Lihuili Hospital (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-02-05
- DOI
- https://doi.org/10.3389/fnagi.2025.1544352
- Citations
- 5
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 6.47
Funders
- Natural Science Foundation of Ningbo Municipality
- Natural Science Foundation of Ningbo
- Medical Science and Technology Project of Zhejiang Province