Interactions between NAD+ metabolism and immune cell infiltration in ulcerative colitis: subtype identification and development of novel diagnostic models
Our study reveals two NAD+ subtypes in UC, identifying four biomarkers for subtyping and two for diagnosis. These findings could suggest potential therapeutic targets and contribute to advancing personalized treatment strategies for UC, potentially improving patient outcomes.
Authors
- He Huang (ORCID: https://orcid.org/0000-0003-4442-5652)
- Huiyang Gao (ORCID: https://orcid.org/0000-0003-0437-7799)
- Linna Gao
- Yuhao Chen (ORCID: https://orcid.org/0000-0002-2629-4292)
- Yao Tian (ORCID: https://orcid.org/0009-0002-3530-3944)
- Linglin Tian
- Leilei Zhu (ORCID: https://orcid.org/0000-0003-4394-8099)
- Jingxiang Han (ORCID: https://orcid.org/0009-0008-4697-1925)
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-05
- DOI
- https://doi.org/10.3389/fimmu.2025.1479421
- Citations
- 3
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Natural Science Foundation of Shanxi Province