IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3
Our work reveals a role for IFNβ in promoting ferroptosis and provides evidence that IFNβ could be used with RSL3 to increase cytotoxic effects in tumor cells.
Authors
- Wei Zhang (ORCID: https://orcid.org/0000-0002-1678-7683)
- Zongyang Yu
- Huiyue Dong (ORCID: https://orcid.org/0000-0003-4107-2150)
- Pengyang Liu (ORCID: https://orcid.org/0000-0003-4675-6906)
- Rong Lin (ORCID: https://orcid.org/0000-0001-9463-8942)
- Ling Zhu (ORCID: https://orcid.org/0000-0003-0437-4096)
- Jun Lü (ORCID: https://orcid.org/0000-0002-7343-9706)
- Hao Zeng (ORCID: https://orcid.org/0000-0002-1267-0509)
- Jingjing Sun
- Qiuyan Chen (ORCID: https://orcid.org/0000-0001-9637-4995)
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Fujian Medical University (CN)
- Xiamen University (CN)
- Wuhan Children's Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-05
- DOI
- https://doi.org/10.3389/fimmu.2025.1535554
- Citations
- 4
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 3.19