Discordance between 90Y-PET/CT(MR)-estimated activity and dose calibrator measured administered activity: an international study in SIRT patients treated with resin and glass microspheres
We observed in patients similar activity discrepancies as reported for vials, with a relative difference of 44 ± 16% between glass and resin <sup>90</sup>Y-loaded microspheres. In <sup>90</sup>Y hepatic radioembolization, the 10% accuracy prerequisite on knowing the administered therapeutic activity is then unlikely to be met.
Authors
- John Olivier Prior (ORCID: https://orcid.org/0000-0003-1429-1374)
- María del Sol Pérez Lago
- Justin Mikell (ORCID: https://orcid.org/0000-0003-0679-7199)
- Clément Bailly (ORCID: https://orcid.org/0000-0001-8313-3287)
- Thomas Carlier (ORCID: https://orcid.org/0000-0002-6932-7322)
- Silvano Gnesin (ORCID: https://orcid.org/0000-0002-6547-3824)
- Niklaus Schaefer (ORCID: https://orcid.org/0000-0002-9732-7696)
- Yuni K. Dewaraja (ORCID: https://orcid.org/0000-0002-3920-6925)
- Maurizio Conti (ORCID: https://orcid.org/0000-0001-8215-4836)
- Thiago Lima (ORCID: https://orcid.org/0000-0002-3105-9270)
Institutions
- Washington University in St. Louis (US)
- University of Michigan (US)
- Luzerner Kantonsspital (CH)
- University of Lausanne (CH)
Publication Details
- Journal
- EJNMMI Physics
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1186/s40658-025-00725-8
- Citations
- 2
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- Agence Nationale de la Recherche