The prevalence of thromboembolic events among COVID-19 patients admitted to a single centre intensive care unit (ICU): an epidemiological study from a Malaysian population

In severely ill COVID-19 patients, TE complications were common, and patients with DVT, PE, stroke, or MI faced increased mortality, even with thromboprophylaxis. Age, obesity, elevated D-Dimer levels, and longer ICU stays were significant predictors of TE events. Considering these findings, a more aggressive approach, combining thromboprophylaxis with enhanced anti-inflammatory treatments, may be necessary for high-risk COVID-19 ICU patients to reduce TE events and mortality.

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Publication Details

Journal
Journal of Pharmaceutical Policy and Practice
Published
2025-02-05
DOI
https://doi.org/10.1080/20523211.2024.2449044
Primary Topic
COVID-19 Clinical Research Studies
Type
article
Field-Weighted Citation Impact
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article

The prevalence of thromboembolic events among COVID-19 patients admitted to a single centre intensive care unit (ICU): an epidemiological study from a Malaysian population

Elizabeth K. Seng, Hanis Hanum Zulkifly, Long Chiau Ming, Khang Wen Goh et al.
Journal of Pharmaceutical Policy and Practice
COVID-19 Clinical Research Studies
article

The prevalence of thromboembolic events among COVID-19 patients admitted to a single centre intensive care unit (ICU): an epidemiological study from a Malaysian population

Elizabeth K. Seng, Hanis Hanum Zulkifly, Long Chiau Ming, Khang Wen Goh, Nur Farhani Mansor, Izzati Abdul Halim Zaki, Mohan Pathmanathan, Lee Chew Kiok, Pakhrur Razi, Tharmini Ravi
article en

Abstract

In severely ill COVID-19 patients, TE complications were common, and patients with DVT, PE, stroke, or MI faced increased mortality, even with thromboprophylaxis. Age, obesity, elevated D-Dimer levels, and longer ICU stays were significant predictors of TE events. Considering these findings, a more aggressive approach, combining thromboprophylaxis with enhanced anti-inflammatory treatments, may be necessary for high-risk COVID-19 ICU patients to reduce TE events and mortality.

Journal of Pharmaceutical Policy and PracticeVol. 18(1)
INTI International University (MY), National Institutes of Health (US), State University of Padang (ID), Hospital Kuala Lumpur (MY), Datta Meghe Institute of Higher Education and Research (IN), Hospital Sungai Buloh (MY), Universiti Teknologi MARA (MY), Sunway University (MY)
Good health and well-being
Openalex Percentile: Top 96%
COVID-19 Clinical Research Studies
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