Agar-Dilution Is Comparable to Broth Dilution for MIC Determination in Streptococcus agalactiae

Agar-dilution is a valid method for high-throughput AMR surveillance of retrospective cohorts (96 isolates per plate) and is critical for identifying emerging GBS resistance trends and informing therapeutic guidelines. However, due to the large number of plates required per antimicrobial, it is impractical for routine clinical diagnostics.

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Publication Details

Journal
Antibiotics
Published
2025-02-05
DOI
https://doi.org/10.3390/antibiotics14020156
Citations
3
Primary Topic
Neonatal and Maternal Infections
Type
article
Field-Weighted Citation Impact
5.64
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article

Agar-Dilution Is Comparable to Broth Dilution for MIC Determination in Streptococcus agalactiae

Juliana Coelho, Caitlin Farley, Edward Portal, Victoria J. Chalker et al.
3 citations
Antibiotics
Neonatal and Maternal Infections
5.64
article

Agar-Dilution Is Comparable to Broth Dilution for MIC Determination in Streptococcus agalactiae

Juliana Coelho, Caitlin Farley, Edward Portal, Victoria J. Chalker, Stephen D. Bentley, Androulla Efstratiou, O. Brad Spiller, Teresa Iannetelli
article en
3 citations

Abstract

Agar-dilution is a valid method for high-throughput AMR surveillance of retrospective cohorts (96 isolates per plate) and is critical for identifying emerging GBS resistance trends and informing therapeutic guidelines. However, due to the large number of plates required per antimicrobial, it is impractical for routine clinical diagnostics.

AntibioticsVol. 14(2)
University Hospital of Wales (GB), Wellcome Sanger Institute (GB), University of Oxford (GB), Chief Scientist Office (GB), Cardiff University (GB)
Openalex Percentile: Top 5%
Neonatal and Maternal Infections
5.64
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