Blood Sample Collection in Randomized Controlled Trials for Biomarker Discovery and Validation: Experience of the PREOPANC-2 Trial
Blood sample collection in the PREOPANC-2 trial had a yield of 96 % before treatment and an overall yield of 87 %. Collection of blood samples for biomarker studies is feasible in a nationwide RCT.
Authors
- Roeland F. de Wilde (ORCID: https://orcid.org/0009-0003-0444-8697)
- Gaby J. Strijk (ORCID: https://orcid.org/0009-0008-8916-2300)
- Eva Versteijne (ORCID: https://orcid.org/0000-0003-3861-5310)
- M. B. van der Kolk
- Casper H.J. van Eijck (ORCID: https://orcid.org/0000-0002-9511-2157)
- Hjalmar C. van Santvoort (ORCID: https://orcid.org/0009-0007-1218-2883)
- Marc G. Besselink (ORCID: https://orcid.org/0000-0003-2650-9350)
- Stefan A.W. Bouwense (ORCID: https://orcid.org/0000-0002-7600-9429)
- Koop Bosscha (ORCID: https://orcid.org/0000-0002-7961-3314)
- G. Kazemier
- Mike S.L. Liem (ORCID: https://orcid.org/0000-0001-8665-1506)
- J. Sven D. Mieog (ORCID: https://orcid.org/0000-0002-3649-8504)
- Jan Willem B. de Groot (ORCID: https://orcid.org/0000-0002-1043-5011)
- Bas Groot Koerkamp (ORCID: https://orcid.org/0000-0003-1917-6973)
- Brigitte C.M. Haberkorn (ORCID: https://orcid.org/0009-0006-6869-7264)
- Geertjan van Tienhoven (ORCID: https://orcid.org/0000-0002-2516-2263)
- Diederik ten Oever
- Laurens V. Beerepoot (ORCID: https://orcid.org/0000-0002-3040-4626)
- Tom M. Karsten
- Gijs A. Patijn
- Sridhar Kandala (ORCID: https://orcid.org/0000-0002-6222-0872)
- Jasper Dumas
- Saskia A. C. Luelmo (ORCID: https://orcid.org/0000-0002-9298-2878)
- Quisette P. Janssen (ORCID: https://orcid.org/0000-0002-9353-8293)
- Martijn W.J. Stommel (ORCID: https://orcid.org/0000-0002-4257-5254)
- A. Bruynzeel (ORCID: https://orcid.org/0000-0002-7542-8920)
- Geert A. Cirkel (ORCID: https://orcid.org/0009-0007-8712-9825)
- Dana A. M. Mustafa (ORCID: https://orcid.org/0000-0003-0644-078X)
- Ignace H. J. T. de Hingh (ORCID: https://orcid.org/0000-0003-3491-4268)
- Marlies L. van Bekkum
- Eileen Mary O'Reilly (ORCID: https://orcid.org/0000-0002-8076-9199)
- Hayley Bos
- Marjolein Y.V. Homs (ORCID: https://orcid.org/0000-0001-9828-2541)
- Esther N. Dekker (ORCID: https://orcid.org/0000-0002-3040-6736)
- B. Bonsing
- Jacob L. van Dam (ORCID: https://orcid.org/0000-0002-6947-9035)
- Mirte Mayke Streppel
- O.R. Busch
- Eva M. M. Verkolf
- Amine Fellah (ORCID: https://orcid.org/0009-0000-1631-7254)
- L. Brouwer-Hol
- Joost J. Nuyttens (ORCID: https://orcid.org/0009-0002-5021-1597)
- P. P. L. O. Coene
- Judith de Vos Geelen
- Johanna W. Wilmink
- A ten Tije
- Vincent B. Nieuwenhuijs (ORCID: https://orcid.org/0000-0001-9311-8208)
- O. J. L. Loosveld
- C. M. Luyer
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- Erasmus MC (NL)
- Erasmus MC Cancer Institute (NL)
- Amsterdam University Medical Centers (NL)
- Cancer Center Amsterdam (NL)
- University of Amsterdam (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1245/s10434-025-16890-0
- Citations
- 2
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- ZonMw
- KWF Kankerbestrijding