Ten Simple Rules for Making a Career Transition from Basic Science to Public Health Research

It is not uncommon for basic scientists to switch into public health research. Such career transitions present a variety of challenges and opportunities and can reinvigorate a career, lead to new skills, and provide the chance to contribute to individual and community health and social justice. Based on our respective experiences switching from applied physics to infectious disease modelling and from evolutionary physiology to cancer prevention and control, we propose ten simple rules intended to help researchers from other disciplines think about a transition to public health research. Together, these rules are largely about navigating between pairs of extremes related to why you want to move in a new direction, how to balance old and new expertise, and balancing humility with the confidence that you are bringing something important to the table. A career transition can also fulfill some of the basic motivators for a research career, including curiosity and a passion to try to solve important problems. Our career transitions proved deeply satisfying. We hope yours will as well.