Pre-exposure to phage particles reduces their antibacterial therapeutic efficacy both in vitro and in vivo
pre-exposure to phage particles may induce phage-neutralization antibodies and inhibit their therapeutic efficacies, delaying recovery or even exacerbating S. aureus-associated dermal abscesses for later treatment.
Authors
- Tingting Feng (ORCID: https://orcid.org/0000-0003-1285-8779)
- Yufeng Yao (ORCID: https://orcid.org/0000-0003-0395-3993)
- Zelin Cui (ORCID: https://orcid.org/0000-0002-2700-5800)
- Lianhui Sun
- Lei Zhong (ORCID: https://orcid.org/0000-0002-2282-9149)
- Ting Zhu (ORCID: https://orcid.org/0000-0003-4149-2710)
- Guangjian Fan (ORCID: https://orcid.org/0000-0003-0684-1380)
- Jingyi He (ORCID: https://orcid.org/0000-0002-3640-3093)
- D Z Xu
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Chest Hospital (CN)
- Shanghai First People's Hospital (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- International Journal of Medical Microbiology
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1016/j.ijmm.2025.151649
- Citations
- 1
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- National Natural Science Foundation of China