Central Dentinogenic Ghost Cell Tumor: A Rare Entity

Odontogenic tumors are rare lesions with varied clinical presentations and behaviors. A dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm that can be classified into central (intraosseous) and peripheral (extraosseous) types, with a central DGCT often presenting as a bone-expanding lesion. We report a case of a multimorbid 66-year-old male patient with a central DGCT presenting as a painless, 3 × 5.3 cm expansile mass in the right mandibular body. The patient underwent radiographic and histologic assessment followed by tumor enucleation under local anesthesia, which revealed classic features of the DGCT, including ghost cells, calcifications, and a low proliferation index, consistent with low malignant potential.

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Publication Details

Journal
Cureus
Published
2025-02-05
DOI
https://doi.org/10.7759/cureus.78556
Primary Topic
Oral and Maxillofacial Pathology
Type
article
Field-Weighted Citation Impact
0.00
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article

Central Dentinogenic Ghost Cell Tumor: A Rare Entity

Munir Nashashibi, Imad Abu El‐Naaj, Amir Farah
Cureus
Oral and Maxillofacial Pathology
article

Central Dentinogenic Ghost Cell Tumor: A Rare Entity

Munir Nashashibi, Imad Abu El‐Naaj, Amir Farah
article en

Abstract

Odontogenic tumors are rare lesions with varied clinical presentations and behaviors. A dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm that can be classified into central (intraosseous) and peripheral (extraosseous) types, with a central DGCT often presenting as a bone-expanding lesion. We report a case of a multimorbid 66-year-old male patient with a central DGCT presenting as a painless, 3 × 5.3 cm expansile mass in the right mandibular body. The patient underwent radiographic and histologic assessment followed by tumor enucleation under local anesthesia, which revealed classic features of the DGCT, including ghost cells, calcifications, and a low proliferation index, consistent with low malignant potential.

CureusVol. 17(2)
Medical College of Wisconsin (US), Poriya Medical Center (IL)
Openalex Percentile: Top 97%
Oral and Maxillofacial Pathology
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