A New Dihydrophenanthrene with Cell Viability Enhancing Activities from Spiranthes sinensis
A new dihydrophenanthrene (Spiranthol B), along with four known compounds, were isolated from Spiranthes sinensis.The new structure was determined by various spectroscopic analyses such as 1D, 2D NMR and HRMS techniques.Its stereochemistry was resolved by using the calculated electronic circular dichroism (ECD).Compounds 1-5 showed their capabilities to attenuate palmitic acid (PA)-induced reductions in MIN6 cells viability with the dosages of 3.125 and 6.25 M.
Authors
- Chengpeng Liu (ORCID: https://orcid.org/0000-0001-6886-6407)
- Xiaopo Zhang (ORCID: https://orcid.org/0000-0003-2614-7425)
- Min Ji
- Yiqiao Wang (ORCID: https://orcid.org/0000-0001-8179-5797)
- Caiyun Zhang (ORCID: https://orcid.org/0000-0002-9570-0207)
- Yiming Wang (ORCID: https://orcid.org/0009-0001-2678-5673)
Institutions
- Hainan Medical University (CN)
Publication Details
- Journal
- Records of Natural Products
- Published
- 2025-02-05
- DOI
- https://doi.org/10.25135/rnp.492.2410.3345
- Primary Topic
- Biological and pharmacological studies of plants
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China