LncRNA CRCMSL interferes in phospholipid unsaturation to suppress colorectal cancer progression via reducing membrane fluidity
Our study illustrated a novel mechanism of CRCMSL-ACC1 axis-associated fatty acid metabolism in CRC progression, providing laboratory evidence for the development of targeted therapies for patients with advanced CRC.
Authors
- Hui Wang (ORCID: https://orcid.org/0009-0005-6936-9281)
- Muhong Jiang
- Wandie Lin
- Weiwei Liu (ORCID: https://orcid.org/0000-0003-4708-8057)
- Yujie Zhang (ORCID: https://orcid.org/0000-0001-7381-2577)
- Lijun Xu (ORCID: https://orcid.org/0000-0001-9515-6128)
- Liang Zhao (ORCID: https://orcid.org/0000-0002-1429-0884)
Institutions
- The First People's Hospital of Shunde (CN)
- Guangzhou Medical University Cancer Hospital (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1016/j.jare.2025.02.003
- Citations
- 7
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 6.55
Funders
- Beijing Xisike Clinical Oncology Research Foundation
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province