Sensitivity enhancement of surface plasmon resonance biosensor with Ti3C2Tx nanosheets

A surface plasmon sensor (SPR) utilizing Ti₃C₂T_x nanosheets is proposed in this work. The findings reveal that sensitivity increases initially and then decreases with the number of deposition cycles. A maximum sensitivity of 3467.8nm RIU⁻¹ is achieved after one deposition cycle, marking a 71.27% improvement over the unmodified sensors. In addition, the shifts in resonant wavelength in-creased from 2.89nm to 6.35nm in the test with a 0.4mg/mL Bovine Serum Albumin (BSA) solution. These results suggest that the Ti₃C₂T_x modification can significantly enhance the sensitivity of SPR biosensor.