Shared Allergenicity in a Lapin-Model of Delayed Htpersensitivity to Gram Negative Protoplasmic Sonicate Proteins PSP

There were shared allergenicity in delayed type hypersensitivity between the protoplasmic sonicate proteins of Pseudomonas aeruginosa with that of Klebsiella oxytoca Mild erythema was noted from 6 to72 hrs post to P. aeruginosa (PSP) in Klebsiella oxytoca PSP primed rabbits (KOPSP).Mild, moderate to high erythema during 6 up to 72 hrs post to injecting KOPSP in PAPSP primed rabbits.Induration of 5 mm at 72 hrs of PAPSP intradermal ID injecting in KOPSP primed rabbits.While Short Research Articleinduration of 6 to 12 mm of KOPSP ID injected to PAPSP primed rabbits.Consenquently there was a high quantitative and /or potency of the allergenic fraction of KO than that of PA.The shared fractions were characterized as delayed allergenicity of bilateral or reciprocal type delayed allergenic nature.Such findings appeared to be novel contribution in bacterial protein allergens, with possible pan shared bacterial families.Preserved protein fraction between these two different gram negative representatives of bacterial families.

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Published
2024-09-20
DOI
https://doi.org/10.9734/aji/2024/v7i1142
Primary Topic
Protein Structure and Dynamics
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article
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article

Shared Allergenicity in a Lapin-Model of Delayed Htpersensitivity to Gram Negative Protoplasmic Sonicate Proteins PSP

Qassim Thewaini, Ibrahim Mohamed Saeed Shnawa, ALGebori HSH
Protein Structure and Dynamics
article

Shared Allergenicity in a Lapin-Model of Delayed Htpersensitivity to Gram Negative Protoplasmic Sonicate Proteins PSP

Qassim Thewaini, Ibrahim Mohamed Saeed Shnawa, ALGebori HSH
article en

Abstract

There were shared allergenicity in delayed type hypersensitivity between the protoplasmic sonicate proteins of Pseudomonas aeruginosa with that of Klebsiella oxytoca Mild erythema was noted from 6 to72 hrs post to P. aeruginosa (PSP) in Klebsiella oxytoca PSP primed rabbits (KOPSP).Mild, moderate to high erythema during 6 up to 72 hrs post to injecting KOPSP in PAPSP primed rabbits.Induration of 5 mm at 72 hrs of PAPSP intradermal ID injecting in KOPSP primed rabbits.While Short Research Articleinduration of 6 to 12 mm of KOPSP ID injected to PAPSP primed rabbits.Consenquently there was a high quantitative and /or potency of the allergenic fraction of KO than that of PA.The shared fractions were characterized as delayed allergenicity of bilateral or reciprocal type delayed allergenic nature.Such findings appeared to be novel contribution in bacterial protein allergens, with possible pan shared bacterial families.Preserved protein fraction between these two different gram negative representatives of bacterial families.

Vol. 7(1)
University of Babylon (IQ), Green University of Bangladesh (BD), Ministry of Higher Education and Scientific Research (IQ)
Zero hunger
Openalex Percentile: Top 78%
Protein Structure and Dynamics
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