Challenges in Diagnosis and Management of Takayasu Arteritis: A Case Report Highlighting Vascular Complications and Delayed Recognition

Takayasu arteritis is a rare systemic inflammatory condition that primarily affects medium and large arteries, mainly in young Asian women with an estimated incidence of 1-2 per million. Diagnosis is challenging due to nonspecific early symptoms, resulting in an insidious clinical course until vascular complications arise. A 30-year female presented with progressive easy fatigue over 4 years. She developed recent visual disturbances, headaches, and dizziness. Examination revealed unrecordable blood pressures and vascular bruits. Imaging revealed vascular involvement including stenosis of arch of aorta and its all branches. The available treatments can ease symptoms and slow progression, but the late diagnosis caused lifelong morbidity, with no procedure to resolve persistent fatigue. TA poses diagnostic challenges due to its nonspecific early symptoms and risk of severe vascular complications. This case highlights the importance of considering TA in young women with vague systemic inflammatory symptoms.

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Publication Details

Journal
Clinical Case Reports
Published
2025-02-01
DOI
https://doi.org/10.1002/ccr3.70174
Citations
2
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
3.04
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Challenges in Diagnosis and Management of Takayasu Arteritis: A Case Report Highlighting Vascular Complications and Delayed Recognition

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article

Challenges in Diagnosis and Management of Takayasu Arteritis: A Case Report Highlighting Vascular Complications and Delayed Recognition

Biraj Niraula, Anil Suvedi, Bindira Adhikari, Polina Dahal, Gaurav Subedi
article en
2 citations

Abstract

Takayasu arteritis is a rare systemic inflammatory condition that primarily affects medium and large arteries, mainly in young Asian women with an estimated incidence of 1-2 per million. Diagnosis is challenging due to nonspecific early symptoms, resulting in an insidious clinical course until vascular complications arise. A 30-year female presented with progressive easy fatigue over 4 years. She developed recent visual disturbances, headaches, and dizziness. Examination revealed unrecordable blood pressures and vascular bruits. Imaging revealed vascular involvement including stenosis of arch of aorta and its all branches. The available treatments can ease symptoms and slow progression, but the late diagnosis caused lifelong morbidity, with no procedure to resolve persistent fatigue. TA poses diagnostic challenges due to its nonspecific early symptoms and risk of severe vascular complications. This case highlights the importance of considering TA in young women with vague systemic inflammatory symptoms.

Clinical Case ReportsVol. 13(2)
Chitwan Medical College (NP)
Good health and well-being
Openalex Percentile: Top 11%
Vasculitis and related conditions
3.04
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