In vitro anticancer effects of frankincense and its nanoemulsions for enhanced cancer cell targeting
The results demonstrate that nanoemulsion-based delivery significantly enhances the bioactivity and cellular uptake of frankincense oil compared to its free form. FO-NEs exhibit potent anticancer activity, particularly against drug-resistant cancer cell lines, suggesting their potential as a viable strategy for improving the therapeutic efficacy of frankincense in cancer treatment.
Authors
- Raghuram Kandimalla (ORCID: https://orcid.org/0000-0002-9202-4071)
- Mohammed Al Hinaai
- Farrukh Aqil (ORCID: https://orcid.org/0000-0002-0081-7251)
- Ashanul Haque (ORCID: https://orcid.org/0000-0002-6780-632X)
- Khalaf M. Alenezi (ORCID: https://orcid.org/0000-0002-8482-2110)
- Aiswarya Chaudhuri (ORCID: https://orcid.org/0000-0002-6045-6590)
- Rayya A. Al-Balushi (ORCID: https://orcid.org/0000-0002-5665-5175)
- Samra Siddiqui
- Ashish Agrawal (ORCID: https://orcid.org/0000-0002-0233-4085)
- Mοhd Saeed (ORCID: https://orcid.org/0000-0003-3443-386X)
- Mohammad Changez (ORCID: https://orcid.org/0000-0001-5304-8962)
- Thuraya Al Harthy
Institutions
- University of Louisville (US)
- University of Ha'il (SA)
- University of Buraimi (OM)
- College of Applied Sciences, Nizwa (OM)
- Indian Institute of Technology BHU (IN)
- Banaras Hindu University (IN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-06
- DOI
- https://doi.org/10.3389/fphar.2025.1403780
- Citations
- 3
- Primary Topic
- Pharmacological Effects of Medicinal Plants
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- Ministry of Higher Education, Research and Innovation