Iodonium(III) Ylide: An Iodoalkylation Reagent with Aryne
A tandem Hexadehydro-Diels-Alder (HDDA)/[2 + 2] cycloaddition/aryl migration reaction of iodonium ylide with tetrayne is described, in which iodonium ylide served as a unique double bond and reacted with aryne to form a four-membered iodonium(III) cycle, then converted to iodoarene after aryl group migration from iodine to adjacent carbon. This strategy allows the efficient construction of fully substituted iodoarene compounds.
Authors
- Huaiji Zheng (ORCID: https://orcid.org/0000-0003-1674-7582)
- Weigang Xu (ORCID: https://orcid.org/0000-0003-4705-0390)
- Sajjad Ali (ORCID: https://orcid.org/0000-0002-6444-5119)
- Zhengshen Wang
- Yuerong Li
- Huilin Li (ORCID: https://orcid.org/0000-0001-8085-8928)
- Pengfei Li (ORCID: https://orcid.org/0009-0009-8114-6207)
- Ke Li (ORCID: https://orcid.org/0000-0002-0243-4510)
- Jie Pan (ORCID: https://orcid.org/0000-0001-9051-9014)
- Zhangwen Kou
Institutions
- Northwest A&F University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1021/acs.joc.4c02892
- Citations
- 1
- Primary Topic
- Oxidative Organic Chemistry Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China