Non-inferiority and vaccine titer-confirmation studies of MMR vaccine (JVC-001; measles AIK-C, mumps RIT4385, and rubella Takahashi strains) in healthy 1-year-old Japanese children
Although the non-inferiority of JVC-001 to currently approved vaccines was not demonstrated for the mumps component, clinical significance and consistent efficacy were indicated. Vaccine titer did not affect immunogenicity. JVC-001 is expected to have a lower risk of aseptic meningitis to currently approved vaccines and raised no new safety signals emerged.
Authors
- Yoshitaka Sogawa (ORCID: https://orcid.org/0000-0003-1621-0929)
- Spencer H. Hamada
- Tetsuo Nakayama (ORCID: https://orcid.org/0000-0002-8685-6007)
- Takafumi Nakatsu
- Asuka Kawamura
- Motoshi Kimata
- Keiji Oe
- Sachiko Sakakibara
Institutions
- Daiichi Sankyo (Germany) (DE)
- Daiichi-Sankyo (Japan) (JP)
- Kitasato Institute Hospital (JP)
Publication Details
- Journal
- Vaccine
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1016/j.vaccine.2024.126698
- Citations
- 3
- Primary Topic
- Virology and Viral Diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Daiichi Sankyo Company
- Daiichi Sankyo Europe