Unveiling the potential of copper-61 vs. gallium-68 for SSTR PET imaging
[<sup>61</sup>Cu]Cu-NOTA-TATE showed similar biodistribution and pharmacokinetics to [<sup>68</sup>Ga]Ga-DOTA-TATE at 1 h p.i., while demonstrating superior imaging characteristics for late PET imaging. These findings demonstrate that [<sup>61</sup>Cu]Cu-NOTA-TATE holds promising characteristics for improving the detection of NETs with increased translational potential.
Authors
- Amílcar Falcão
- Alexandra I. Fonseca (ORCID: https://orcid.org/0000-0003-1924-178X)
- Célia Gomes (ORCID: https://orcid.org/0000-0002-7497-4129)
- Ivanna Hrynchak (ORCID: https://orcid.org/0000-0002-1671-7861)
- José Sereno (ORCID: https://orcid.org/0000-0002-9607-6653)
- Francisco Alvès (ORCID: https://orcid.org/0000-0001-8054-4267)
- Antero Abrunhosa (ORCID: https://orcid.org/0000-0002-4145-854X)
- Sara F.F. Almeida (ORCID: https://orcid.org/0000-0001-9018-2220)
- Hugo R. S. Ferreira
Institutions
- Polytechnic Institute of Coimbra (PT)
- Escola Superior de Tecnologia da Saúde de Coimbra (PT)
- University of Coimbra (PT)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1007/s00259-025-07116-2
- Citations
- 2
- Primary Topic
- Radiopharmaceutical Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- Universidade de Coimbra
- Fundação para a Ciência e a Tecnologia