Exploring molecular disparities of H-type vasculature endothelial cells in osteonecrosis of the femoral head through single-cell analysis
H_ECs show molecular differences compared to other endothelial cells. Ferroptosis and parthanatos contribute to the demise of H_ECs in ONFH, with pericytes and fibroblasts supporting H_EC angiogenesis.
Authors
- Shi Wei (ORCID: https://orcid.org/0000-0003-4417-593X)
- Kai Zhang (ORCID: https://orcid.org/0000-0002-7877-4538)
- Zhijun Li (ORCID: https://orcid.org/0000-0002-1378-791X)
- Huafeng Zhang (ORCID: https://orcid.org/0000-0001-9285-2478)
- Dong Li
- Xinyu Liang (ORCID: https://orcid.org/0009-0001-6233-0297)
- Qian Xu (ORCID: https://orcid.org/0000-0002-5007-3414)
- Hui Li (ORCID: https://orcid.org/0009-0009-0637-4437)
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Tianjin Medical University General Hospital (CN)
Publication Details
- Journal
- BMC Musculoskeletal Disorders
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1186/s12891-024-08267-3
- Citations
- 1
- Primary Topic
- Bone and Joint Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Natural Science Foundation of Tianjin City