Clinical repercussions after liberal volume replacement in the intraoperative period of cancer patients in a Hospital Unit in the Amazon

During the perioperative period, intravascular volume management becomes crucial to achieve better postoperative outcomes. Maintenance of euvolemia is critical to ensure adequate tissue perfusion, since hypervolemia has been associated with higher rates of postoperative morbidity. One of the main challenges in managing surgical volume lies in intravascular monitoring. Despite the use of essential tools such as non-invasive blood pressure cuffs and heart rate monitoring, significant challenges persist due to difficulties in accurately measuring fluid losses, varied cardiovascular responses to anesthesia, and the absence of standardized assessment protocols for anesthetized patients. Given the critical role of adequate volume replacement in cancer patients undergoing medium-sized urologic surgeries, this study aims to identify potential adverse clinical consequences associated with volume replacement therapy in postoperative ICU patients undergoing radical prostatectomy and radical nephrectomy in an oncology referral center in the Brazilian Amazon. This prospective, descriptive and exploratory study will be carried out from August 2023 to August 2024 at the Amazonas Oncological Control Center Foundation (FCECON). The research seeks to elucidate specific adverse clinical outcomes related to fluid management in cancer patients undergoing these surgical procedures.