Sprouting and network data assessed in the chicken aortic ring assay under stimulation with human adipose-derived stem cell secretomes harvested from single cells or spheroids of different sizes

The aortic ring assay is widely used to assess the angiogenic modulation evoked by various drugs. However, different parameters are used as readouts and there is no congruence in terminology. In addition, some researchers use one set of parameters, and other researchers choose parameters that overlap to some extent, but miss a part of these parameters, rendering a direct comparison of the readouts and results difficult [1]. Therefore, we present data acquired in the chicken aortic ring assay that cover the full spectrum of possible readouts - exemplified by stimulation with secretomes harvested from human adipose-derived stem cells, cultivated either as single cell monolayer culture or as 3D spheroids, sized 250 cells/spheroid or 8000 cells/spheroid, respectively.

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Publication Details

Journal
Data in Brief
Published
2025-02-05
DOI
https://doi.org/10.1016/j.dib.2025.111371
Citations
2
Primary Topic
3D Printing in Biomedical Research
Type
article
Field-Weighted Citation Impact
1.35

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article

Sprouting and network data assessed in the chicken aortic ring assay under stimulation with human adipose-derived stem cell secretomes harvested from single cells or spheroids of different sizes

Julia von Atzigen, Johanna Buschmann, Pietro Giovanoli, Maurizio Calcagni et al.
2 citations
Data in Brief
3D Printing in Biomedical Research
1.35
article

Sprouting and network data assessed in the chicken aortic ring assay under stimulation with human adipose-derived stem cell secretomes harvested from single cells or spheroids of different sizes

Julia von Atzigen, Johanna Buschmann, Pietro Giovanoli, Maurizio Calcagni, Petra Wolint, Iris Miescher, Silvan Hofmann, Roland Böni, Maximilian Y. Emmert
article en
2 citations

Abstract

The aortic ring assay is widely used to assess the angiogenic modulation evoked by various drugs. However, different parameters are used as readouts and there is no congruence in terminology. In addition, some researchers use one set of parameters, and other researchers choose parameters that overlap to some extent, but miss a part of these parameters, rendering a direct comparison of the readouts and results difficult [1]. Therefore, we present data acquired in the chicken aortic ring assay that cover the full spectrum of possible readouts - exemplified by stimulation with secretomes harvested from human adipose-derived stem cells, cultivated either as single cell monolayer culture or as 3D spheroids, sized 250 cells/spheroid or 8000 cells/spheroid, respectively.

Data in BriefVol. 59
University of Zurich (CH), Humboldt-Universität zu Berlin (DE), Swiss Institute for Regenerative Medicine (CH), University Hospital of Zurich (CH), Deutsches Herzzentrum der Charité (DE), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Freie Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
National Science Foundation, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Hartmann Müller-Stiftung für Medizinische Forschung
Zero hunger
Openalex Percentile: Top 22%
3D Printing in Biomedical Research
1.35
DOIOpen Access PDFOpenAlex
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