Chemo-proteomics reveals dihydrocaffeic acid exhibits anti-inflammation effects via Transaldolase 1 mediated PERK-NF-κB pathway
This study provide support for the potential advancement of DA for use as a therapeutic agent for the treatment of acute pneumonia and inflammation-associated diseases.
Authors
- Wenhua Kuang (ORCID: https://orcid.org/0000-0002-5005-2330)
- Ling Huang (ORCID: https://orcid.org/0000-0002-0887-5544)
- Xinzhou Zhang (ORCID: https://orcid.org/0000-0003-1082-2625)
- Ying Zhang (ORCID: https://orcid.org/0000-0003-4082-5026)
- Huiying Li (ORCID: https://orcid.org/0000-0003-3082-2219)
- Jigang Wang (ORCID: https://orcid.org/0000-0002-0575-0105)
- Xiao Wei (ORCID: https://orcid.org/0000-0002-2916-4821)
- Huan Tang (ORCID: https://orcid.org/0000-0002-9098-0684)
- Guanjun Li
- Peili Wang (ORCID: https://orcid.org/0000-0002-3179-8364)
- Quy Tuan Du (ORCID: https://orcid.org/0009-0004-8455-7910)
Institutions
- Henan University (CN)
- Guangdong Pharmaceutical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Southern University of Science and Technology (CN)
- Dongguan People’s Hospital (CN)
- Xiyuan Hospital (CN)
- China Academy of Chinese Medical Sciences (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Shenzhen Second People's Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1186/s12964-024-01958-3
- Citations
- 8
- Primary Topic
- Biomedical Research and Pathophysiology
- Type
- article
- Field-Weighted Citation Impact
- 11.77
Funders
- National Natural Science Foundation of China
- China Academy of Chinese Medical Sciences
- Science, Technology and Innovation Commission of Shenzhen Municipality
- National Key Research and Development Program of China
- Basic and Applied Basic Research Foundation of Guangdong Province