Lymph node yield does not affect the cancer-specific survival of patients with T1 colorectal cancer: a population-based retrospective study of the U.S. database and a Chinese registry
Our findings suggest that LNY is not significantly associated with CSS in patients with T1 CRC, challenging the necessity of adhering to the 12-node benchmark for early-stage disease. Instead, factors such as tumor biology, LNM, and patient demographics may be more relevant in determining survival outcomes. Further prospective studies are needed to validate these findings and refine guidelines for lymph node assessment in early-stage CRC.
Authors
- Zhixun Zhao (ORCID: https://orcid.org/0000-0002-6388-3838)
- Zhaoxu Zheng (ORCID: https://orcid.org/0000-0002-6585-5785)
- Fei Huang (ORCID: https://orcid.org/0000-0003-3263-0675)
- Fuqiang Zhao (ORCID: https://orcid.org/0000-0003-0676-8371)
- Jiyun Li (ORCID: https://orcid.org/0000-0003-4877-8199)
- Ruoxi Tian
- Qian Liu (ORCID: https://orcid.org/0000-0003-2510-3113)
- Pu Cheng (ORCID: https://orcid.org/0000-0002-0226-3467)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
Publication Details
- Journal
- International Journal of Colorectal Disease
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1007/s00384-025-04816-x
- Citations
- 1
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.52