Use of hydroxyurea in French-speaking Sub-Saharan Africa
The hydroxyurea is a save, affordable and essential medicine for sickle cell disease (SCD), reducing painful crises and mortality. To foster the prescription of hydroxyurea for patients with SCD in sub-Saharan African countries, the scientific advisory board of Drep.Afrique, a non-governmental organization dedicated to SCD in Africa, has developed a therapeutic guideline well suited to conditions on the ground. These guidelines answer three essential questions: which patients should be prioritized for treatment with hydroxyurea, which dose should be used, and what follow-up should be implemented in those low-resources countries? The guidelines are given as in a concise document for easy use by practitioners on the ground, available in English and in French.
Authors
- Mariane de Montalembert (ORCID: https://orcid.org/0000-0002-4900-4753)
- Frédéric Galactéros (ORCID: https://orcid.org/0000-0001-8130-1208)
- Ibrahima Diagne (ORCID: https://orcid.org/0000-0003-0598-7281)
- Léon Tshilolo (ORCID: https://orcid.org/0000-0002-6318-0227)
- Françoise Bernaudin (ORCID: https://orcid.org/0000-0001-5184-8288)
- Anne Corbasson
- Saliou Diop (ORCID: https://orcid.org/0000-0002-2354-3839)
- Olivier Hermine (ORCID: https://orcid.org/0000-0003-2574-3874)
- Charlotte Eposse
- Brigitte Ranque (ORCID: https://orcid.org/0000-0001-8549-2275)
- Éléonore Kafando
- C. Vodouhé
- Ahoéfa Vovor
- Dapa A. Diallo
- Indou Dème-Ly
- J Arlet
- Agnès Lainé
- Binta Coulibaly
Institutions
- Université Gaston Berger (SN)
- Hôpital Necker-Enfants Malades (FR)
- Université Joseph Ki-Zerbo (BF)
- University of Douala (CM)
- Université Paris Cité (FR)
- Kinshasa General Hospital (CD)
- Institut des Mondes Africains (FR)
- University of Bamako (ML)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Européen Georges-Pompidou (FR)
- Centro Universitário de Franca (BR)
- Université des Sciences, des Techniques et des Technologies de Bamako (ML)
- Centre Hospitalier National Universitaire de Fann (SN)
- Hôpital Intercommunal de Créteil (FR)
- University of Lomé (TG)
- Cheikh Anta Diop University (SN)
Publication Details
- Journal
- Annals of Hematology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1007/s00277-024-06180-2
- Citations
- 3
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.88