A New Method for Comprehensive Analysis of Benzodiazepine, Opioid, and Propofol Interactions and Dose Selection Rationales in Gastrointestinal Endoscopy Sedation
This study used a clinically relevant method and model simulation to determine suitable sedation regimens for use in gastrointestinal endoscopy. A balanced propofol, midazolam, and an opioid should be used. The AUC method was capable of providing objective assessments for model selection.
Authors
- Mei‐Yung Tsou (ORCID: https://orcid.org/0000-0002-6740-4080)
- I-Ting Kuo (ORCID: https://orcid.org/0000-0001-8676-6477)
- Weng-Kuei Chang
- Chien‐Kun Ting (ORCID: https://orcid.org/0000-0002-3156-8139)
- Jing-Yang Liou (ORCID: https://orcid.org/0000-0002-9741-2604)
- Hsin‐Yi Wang (ORCID: https://orcid.org/0000-0001-8527-3320)
Institutions
- Fu Jen Catholic University (TW)
- National Yang Ming Chiao Tung University (TW)
- National Central University (TW)
- Taipei Veterans General Hospital (TW)
- Cardinal Tien Hospital (TW)
Publication Details
- Journal
- Anesthesia & Analgesia
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1213/ane.0000000000007263
- Citations
- 4
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 8.76