Pediatric DTC Genetic Testing for Adult-Onset Inherited Cancer Risk: The Perspectives of High-Risk Parents
Few high-risk parents utilized DTC testing for their children. Parents generally preferred the prospect of clinical testing, but some believed DTC testing should be an option available to families. Clinicians should discuss the risks and benefits of pediatric genetic testing, including DTC, with high-risk parents. This may facilitate more informed decision-making that minimizes potential harms.
Authors
- Madison K. Kilbride (ORCID: https://orcid.org/0000-0002-8923-9944)
- Jamie Brower (ORCID: https://orcid.org/0000-0003-1614-8934)
- Beth N. Peshkin (ORCID: https://orcid.org/0000-0002-2997-4701)
- Jada G. Hamilton (ORCID: https://orcid.org/0000-0001-8377-4666)
- C.M. Salafia (ORCID: https://orcid.org/0009-0004-0478-6124)
- Hannah Ovadia
- Marcelo M. Sleiman
- Beth A. Tarini (ORCID: https://orcid.org/0000-0003-4272-8668)
- Sarah Vittone (ORCID: https://orcid.org/0000-0002-7110-0805)
- Benjamin S. Wilfond (ORCID: https://orcid.org/0000-0002-2671-9860)
- Susan M. Domchek (ORCID: https://orcid.org/0000-0002-5914-7272)
- Rosalba Sacca
- Lainie Friedman Ross (ORCID: https://orcid.org/0000-0002-7395-3000)
- Claudine J. Isaacs (ORCID: https://orcid.org/0000-0002-9646-1260)
- Mary Rose Yockel
- Kenneth P. Tercyak (ORCID: https://orcid.org/0000-0003-0274-556X)
- Muriel R. Statman
Institutions
- Seattle Children's Hospital (US)
- Memorial Sloan Kettering Cancer Center (US)
- Children's National (US)
- University of America (US)
- Georgetown University (US)
- University of Utah (US)
- Georgetown University Medical Center (US)
- University of Rochester Medical Center (US)
- University of Rochester (US)
- University of Pennsylvania (US)
- Catholic University of America (US)
Publication Details
- Journal
- Public Health Genomics
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1159/000543913
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Cancer Institute