Histones are critical toxic factors in gut lymph of severe acute pancreatitis: Neutralization by baicalin and baicalein for protection
Histones are key toxic factors in the gut lymph of SAP and their antagonism by baicalin and baicalein offers a novel therapeutic strategy.
Authors
- David G. Fernig (ORCID: https://orcid.org/0000-0003-4875-4293)
- Peter Szatmary (ORCID: https://orcid.org/0000-0002-7454-9851)
- John A. Windsor (ORCID: https://orcid.org/0000-0001-5995-5432)
- Jiwon Hong (ORCID: https://orcid.org/0000-0003-0936-3281)
- Wenhao Cai
- Robert Michael Sutton (ORCID: https://orcid.org/0000-0002-2771-8931)
- Shiyu Liu (ORCID: https://orcid.org/0000-0002-8922-331X)
- Lan Li (ORCID: https://orcid.org/0000-0001-8401-4001)
- Tingting Liu (ORCID: https://orcid.org/0000-0003-0027-0812)
- Qing Xia (ORCID: https://orcid.org/0000-0003-4373-2722)
- Qiqi Wang (ORCID: https://orcid.org/0000-0002-7181-148X)
- Lijia Huang (ORCID: https://orcid.org/0000-0003-2818-940X)
- Wenjuan Luo (ORCID: https://orcid.org/0000-0003-3582-1215)
- Wei Huang (ORCID: https://orcid.org/0000-0002-5791-2444)
- Yongzi Wu
- Anthony Philips
Institutions
- University of Liverpool (GB)
- University of Auckland (NZ)
- Sichuan University (CN)
- Auckland University of Technology (NZ)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1016/j.phymed.2025.156474
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- National Natural Science Foundation of China
- Department of Science and Technology of Sichuan Province
- Health Commission of Sichuan Province
- Sichuan Province Science and Technology Support Program
- West China Hospital, Sichuan University