Lactobacillus rhamnosus GG ameliorates atherosclerosis via suppression of oxidative stress and inflammation by reshaping the gut microbiota
LGG significantly attenuates AS by reducing oxidative stress and inflammation probably via activating the Nrf2/HO-1 pathway. Remarkably, LGG modulates gut microbiota, further enhancing its protective efficacy against AS.
Authors
- Jian Liu (ORCID: https://orcid.org/0000-0003-3101-7553)
- Shaobin Jia (ORCID: https://orcid.org/0000-0002-8545-1067)
- Zhixia Bai (ORCID: https://orcid.org/0000-0002-7099-6953)
- Ru Yan
- Hao Wang (ORCID: https://orcid.org/0000-0002-5776-8681)
- Ting Wang (ORCID: https://orcid.org/0000-0003-2222-5211)
- Yiwei Li (ORCID: https://orcid.org/0000-0002-4444-9286)
- Liting Wang (ORCID: https://orcid.org/0000-0001-6146-2549)
- Xiaoxia Zhang (ORCID: https://orcid.org/0000-0002-4580-493X)
- Yuanyuan Liu (ORCID: https://orcid.org/0000-0003-2450-3289)
- Libo Yang (ORCID: https://orcid.org/0000-0003-2643-7086)
- Yajuan Liu (ORCID: https://orcid.org/0000-0002-6897-8561)
- Wenke Shen
- Huiyan Ma
- Junbai Ma
Institutions
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- Biochemical and Biophysical Research Communications
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1016/j.bbrc.2025.151417
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Ningxia Province