CRISPR-dCas9 Activation of TSG-6 in MSCs Modulates the Cargo of MSC-Derived Extracellular Vesicles and Attenuates Inflammatory Responses in Human Intervertebral Disc Cells In Vitro

Authors

Wolfgang Hitzl (ORCID: https://orcid.org/0000-0002-7696-1479)
Karin Wuertz‐Kozak (ORCID: https://orcid.org/0000-0002-3281-4629)
Varun Puvanesarajah (ORCID: https://orcid.org/0000-0002-3296-6403)
Stefan Schulze (ORCID: https://orcid.org/0000-0002-4771-7987)
Addisu Mesfin (ORCID: https://orcid.org/0000-0003-0076-4185)
G. Wagner
Iker Martinez-Zalbidea
Nea Bergendahl

Institutions

Rochester Institute of Technology (US)
Georgetown University (US)
Paracelsus Medical University (AT)
MedStar Georgetown University Hospital (US)
University of Rochester Medical Center (US)
Schön Klinik München Harlaching (DE)

Publication Details

Journal: Cellular and Molecular Bioengineering
Published: 2025-02-01
DOI: https://doi.org/10.1007/s12195-025-00843-4
Citations: 9
Primary Topic: Extracellular vesicles in disease
Type: article
Field-Weighted Citation Impact: 7.25

Funders

University of Rochester
Paracelsus Medizinische Privatuniversität
National Institutes of Health
Medical Center, University of Rochester
National Institute of Arthritis and Musculoskeletal and Skin Diseases

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article

CRISPR-dCas9 Activation of TSG-6 in MSCs Modulates the Cargo of MSC-Derived Extracellular Vesicles and Attenuates Inflammatory Responses in Human Intervertebral Disc Cells In Vitro

Wolfgang Hitzl, Karin Wuertz‐Kozak, Varun Puvanesarajah, Stefan Schulze et al.

Feb 1, 2025

9 citations

Cellular and Molecular Bioengineering

Extracellular vesicles in disease

7.25

article

CRISPR-dCas9 Activation of TSG-6 in MSCs Modulates the Cargo of MSC-Derived Extracellular Vesicles and Attenuates Inflammatory Responses in Human Intervertebral Disc Cells In Vitro

Wolfgang Hitzl, Karin Wuertz‐Kozak, Varun Puvanesarajah, Stefan Schulze, Addisu Mesfin, G. Wagner, Iker Martinez-Zalbidea, Nea Bergendahl

February 1, 2025article en

9 citations

Abstract

No abstract available for this paper.

Cellular and Molecular BioengineeringVol. 18(1)

Rochester Institute of Technology (US), Georgetown University (US), Paracelsus Medical University (AT), MedStar Georgetown University Hospital (US), University of Rochester Medical Center (US), Schön Klinik München Harlaching (DE)

University of Rochester, Paracelsus Medizinische Privatuniversität, National Institutes of Health, Medical Center, University of Rochester, National Institute of Arthritis and Musculoskeletal and Skin Diseases

Openalex Percentile: Top 3%

Extracellular vesicles in disease

7.25

DOI Open Access PDF OpenAlex

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