Cancer-associated fibroblast-derived COL17A1 promotes gemcitabine resistance and tumorigenesis in pancreatic cancer cells by interacting with ACTN4
CAFs-derived COL17A1 promoted GEM resistance and tumorigenesis in PC by interacting with ACTN4, suggesting a new method for overcoming GEM resistance in PC.
Authors
- Rongyu Shi
- Wei Du (ORCID: https://orcid.org/0000-0001-6047-525X)
- Chengcheng Zhong
- Ning Zhang (ORCID: https://orcid.org/0000-0003-3094-9826)
- Han Li (ORCID: https://orcid.org/0000-0002-5755-2880)
- Xi Yang (ORCID: https://orcid.org/0000-0001-8630-5945)
- Zhong Hu (ORCID: https://orcid.org/0000-0001-6775-4489)
Institutions
- Xuzhou Medical College (CN)
- First Hospital of Jiaxing (CN)
- Jishan County People's Hospital
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1007/s12672-025-01825-8
- Citations
- 4
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 4.18