Late-Onset Urticarial and Erythema Multiforme-Like Eruption Following SARS-CoV-2 Infection

Although SARS-CoV-2 primarily targets the upper respiratory system, its evolving clinical profile has revealed a diverse range of manifestations across multiple organ systems. Emerging evidence increasingly highlights various skin manifestations associated with the virus. This report details the case of a patient who developed a rapidly progressive urticarial dermatosis, characterized by both urticarial and erythema multiforme-like features, five weeks after a SARS-CoV-2 infection. Our objective is to underscore the histologic patterns of late-onset skin eruptions related to SARS-CoV-2, focusing on dermatological complications that can arise beyond the acute phase of the infection.

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Publication Details

Journal
Cureus
Published
2025-02-05
DOI
https://doi.org/10.7759/cureus.78547
Primary Topic
Dermatological and COVID-19 studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Late-Onset Urticarial and Erythema Multiforme-Like Eruption Following SARS-CoV-2 Infection

Barbara S Suening, Michael Glover, Albert Starr, Molly E Boyko
Cureus
Dermatological and COVID-19 studies
article

Late-Onset Urticarial and Erythema Multiforme-Like Eruption Following SARS-CoV-2 Infection

Barbara S Suening, Michael Glover, Albert Starr, Molly E Boyko
article en

Abstract

Although SARS-CoV-2 primarily targets the upper respiratory system, its evolving clinical profile has revealed a diverse range of manifestations across multiple organ systems. Emerging evidence increasingly highlights various skin manifestations associated with the virus. This report details the case of a patient who developed a rapidly progressive urticarial dermatosis, characterized by both urticarial and erythema multiforme-like features, five weeks after a SARS-CoV-2 infection. Our objective is to underscore the histologic patterns of late-onset skin eruptions related to SARS-CoV-2, focusing on dermatological complications that can arise beyond the acute phase of the infection.

CureusVol. 17(2)
Inova Fairfax Hospital (US), University of Florida (US), Carolina Urologic Research Center (US), Edward Via College of Osteopathic Medicine (US), Florida College (US)
Openalex Percentile: Top 95%
Dermatological and COVID-19 studies
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Late-Onset Urticarial and Erythema Multiforme-Like Eruption Following SARS-CoV-2 Infection — Barbara S Suening, Michael Glover, et al. · Cureus (2025) | TGRS Research Map | TGRS