Sex-Specific Association between Anatomic Variants of the Circle of Willis and Intracranial Aneurysms in Individuals with a Familial Predisposition
Women with intracranial aneurysms identified at screening less frequently had a normal anterior part of the CoW compared with those without aneurysms. Additionally, individuals with aneurysms more often had anterior communicating artery hypoplasia or absence, which association was not sex-specific. These anatomic variations may enhance the effectiveness of screening for intracranial aneurysms.
Authors
- Iris N. Vos
- Ynte M. Ruigrok (ORCID: https://orcid.org/0000-0002-5396-2989)
- Irene C. van der Schaaf (ORCID: https://orcid.org/0000-0002-2588-264X)
- Birgitta K. Velthuis (ORCID: https://orcid.org/0000-0002-2542-9474)
- Mireille R. E. Velthuis
- Phebe J. Groenheide
- Marloes H.A. Nanninga
- Denise A.M. van Strien
Institutions
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-02-05
- DOI
- https://doi.org/10.3174/ajnr.a8690
- Citations
- 1
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Hartstichting
- H2020 European Research Council