A Rare Case of Hepatocellular Carcinoma Presenting as Cervical Lymph Node Metastases and Review of the Literature

Hepatocellular carcinoma (HCC) is a leading cause of cancer morbidity and mortality worldwide. Common sites of metastases include the lungs, regional lymph nodes, bone, and adrenal glands. Although rare, distant metastases to the cervical lymph nodes have been reported. With better therapies for viral hepatitis, there has been a shift in the landscape of chronic liver disease and the development of HCC with rising prevalence of HCC attributable to metabolic dysfunction-associated steatotic liver disease. In this study, we describe a case of metastatic HCC presenting as cervical lymphadenopathy in a patient with metabolic dysfunction-associated steatotic liver disease in the absence of cirrhosis.

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Publication Details

Journal
ACG Case Reports Journal
Published
2025-02-01
DOI
https://doi.org/10.14309/crj.0000000000001620
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

A Rare Case of Hepatocellular Carcinoma Presenting as Cervical Lymph Node Metastases and Review of the Literature

Yinong Wang, Igor Stukalin, Bryce Tkachuk, Stephen E. Congly
ACG Case Reports Journal
Hepatocellular Carcinoma Treatment and Prognosis
article

A Rare Case of Hepatocellular Carcinoma Presenting as Cervical Lymph Node Metastases and Review of the Literature

Yinong Wang, Igor Stukalin, Bryce Tkachuk, Stephen E. Congly
article en

Abstract

Hepatocellular carcinoma (HCC) is a leading cause of cancer morbidity and mortality worldwide. Common sites of metastases include the lungs, regional lymph nodes, bone, and adrenal glands. Although rare, distant metastases to the cervical lymph nodes have been reported. With better therapies for viral hepatitis, there has been a shift in the landscape of chronic liver disease and the development of HCC with rising prevalence of HCC attributable to metabolic dysfunction-associated steatotic liver disease. In this study, we describe a case of metastatic HCC presenting as cervical lymphadenopathy in a patient with metabolic dysfunction-associated steatotic liver disease in the absence of cirrhosis.

ACG Case Reports JournalVol. 12(2)
University of Calgary (CA)
Good health and well-being
Openalex Percentile: Top 97%
Hepatocellular Carcinoma Treatment and Prognosis
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