Differential roles of Alzheimer's disease plasma biomarkers in stepwise biomarker‐guided diagnostics
Plasma NfL could screen for cognitive impairment. p-tau217 reliably detects AD pathology, regardless of diagnosis. p-tau217 and GFAP predict prognosis in ACS. Each plasma biomarker plays a distinct role in stepwise AD diagnostics.
Authors
- Yeshin Kim (ORCID: https://orcid.org/0000-0002-4643-5478)
- Sung Hoon Kang (ORCID: https://orcid.org/0000-0002-9156-3348)
- Min Young Chun (ORCID: https://orcid.org/0000-0003-3731-6132)
- Theresa A. Day
- Duk Lyul Na (ORCID: https://orcid.org/0000-0002-0098-7592)
- Fernando González‐Ortiz (ORCID: https://orcid.org/0000-0001-7897-9456)
- Jun Pyo Kim
- Ko Woon Kim (ORCID: https://orcid.org/0000-0002-4564-9714)
- Hyemin Jang (ORCID: https://orcid.org/0000-0003-3152-1274)
- Jihwan Yun (ORCID: https://orcid.org/0000-0002-2436-4947)
- Si Eun Kim (ORCID: https://orcid.org/0000-0003-0429-5486)
- Chi‐Hun Kim (ORCID: https://orcid.org/0000-0001-8167-4530)
- Han Jo Kim (ORCID: https://orcid.org/0000-0001-7880-690X)
- Jaeho Kim (ORCID: https://orcid.org/0000-0003-3770-2359)
- Heejin Yoo (ORCID: https://orcid.org/0000-0003-4341-6906)
- Soo Hyun Cho (ORCID: https://orcid.org/0000-0002-4262-1468)
- Sang Won Seo (ORCID: https://orcid.org/0000-0003-2568-0797)
- Eun Hye Lee (ORCID: https://orcid.org/0000-0003-2570-3442)
- Daeun Shin (ORCID: https://orcid.org/0000-0003-4834-1026)
- Nicholas J. Ashton
- Yeo Jin Kim
- Na Yeon Jung
- Henrik Zetterberg
- Kaj Blennow
Institutions
- University of Science and Technology of China (CN)
- University of Wisconsin–Madison (US)
- Hallym University (KR)
- Eli Lilly (United States) (US)
- King's College London (GB)
- Yonsei University (KR)
- Hong Kong University of Science and Technology (HK)
- Soonchunhyang University (KR)
- Severance Hospital (KR)
- Korea University Medical Center (KR)
- Stavanger University Hospital (NO)
- Sahlgrenska University Hospital (SE)
- Samsung Medical Center (KR)
- Seoul National University Hospital (KR)
- Centre for Mental Health (GB)
- Sorbonne Université (FR)
- Sacred Heart Hospital (NG)
- Chonnam National University Hospital (KR)
- Inje University Haeundae Paik Hospital (KR)
- Kangwon National University Hospital (KR)
- Pitié-Salpêtrière Hospital (FR)
- UK Dementia Research Institute (GB)
- Jeonbuk National University Hospital (KR)
- Sacred Heart Hospital (US)
- Kangdong Sacred Heart Hospital (KR)
- Pusan National University Yangsan Hospital (KR)
- Hallym University Dongtan Sacred Heart Hospital (KR)
- National Hospital for Neurology and Neurosurgery (GB)
- Institut du Cerveau (FR)
- Hallym University Sacred Heart Hospital (KR)
- Yonsei University Health System (KR)
- University College London (GB)
- Bucheon University (KR)
- Jeonbuk National University (KR)
- Sungkyunkwan University (KR)
- University of Gothenburg (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/alz.14526
- Citations
- 16
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 23.54
Funders
- Alzheimer's Association
- Alzheimer's Drug Discovery Foundation
- Eli Lilly and Company
- Familjen Erling-Perssons Stiftelse
- Cure Alzheimer's Fund
- Demensförbundet
- Stiftelsen för Gamla Tjänarinnor
- EU Joint Programme – Neurodegenerative Disease Research
- Korea Dementia Research Center
- National Institute for Health and Care Research
- University College London
- European Commission
- National Research Foundation
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Hjärnfonden
- Vetenskapsrådet
- Ministry of Science and ICT, South Korea
- UK Dementia Research Institute
- Fondation pour la Recherche sur Alzheimer
- Samsung
- Avid Radiopharmaceuticals
- HORIZON EUROPE Framework Programme
- Korea National Institute of Health
- Institute for Information and Communications Technology Promotion