Evaluation of causal relationships between genetic liability to inflammatory bowel disease and autism spectrum disorder by Mendelian randomization analysis
Our findings indicate genetic predisposition to ASD might not increase the risk of IBD, whereas genetic liability to IBD is associated with an increased risk of ASD. Further investigations using more powerful datasets are warranted.
Authors
- Huihuan Wu (ORCID: https://orcid.org/0000-0002-2044-785X)
- Rui Jiang (ORCID: https://orcid.org/0000-0003-2677-3047)
- Qi Yang (ORCID: https://orcid.org/0000-0001-8267-2334)
- Hao Chen (ORCID: https://orcid.org/0000-0003-4339-3441)
- Jingwei Li (ORCID: https://orcid.org/0000-0001-6575-9032)
- Weihong Sha
- Wentao Huang (ORCID: https://orcid.org/0000-0002-7872-8996)
- Ruijie Zeng (ORCID: https://orcid.org/0000-0002-9803-0157)
- Zewei Zhuo (ORCID: https://orcid.org/0000-0001-6644-0111)
- Felix W. Leung
Institutions
- University of California, Los Angeles (US)
- VA Sepulveda Ambulatory Care Center (US)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- Dialogues in Clinical Neuroscience
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1080/19585969.2025.2460798
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- Natural Science Foundation of Guangdong Province for Distinguished Young Scholars
- Basic and Applied Basic Research Foundation of Guangdong Province