Statin is associated with higher cortical thickness in early Alzheimer's disease

Statin use is associated with greater cortical thickness in older adults, particularly in those with MCI. These findings suggest that statins may have neuroprotective effects, potentially mitigating neurodegenerative changes in early cognitive decline. Further research with larger cohorts and longer follow-up periods is needed to confirm these findings and understand the mechanisms involved.

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Publication Details

Journal
Experimental Gerontology
Published
2025-02-15
DOI
https://doi.org/10.1016/j.exger.2025.112698
Citations
2
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
2.33
Controls
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article

Statin is associated with higher cortical thickness in early Alzheimer's disease

Yu‐Ming Kong, Yufei Zheng, Huiying Gu
2 citations
Experimental Gerontology
Alzheimer's disease research and treatments
2.33
article

Statin is associated with higher cortical thickness in early Alzheimer's disease

Yu‐Ming Kong, Yufei Zheng, Huiying Gu
article en
2 citations

Abstract

Statin use is associated with greater cortical thickness in older adults, particularly in those with MCI. These findings suggest that statins may have neuroprotective effects, potentially mitigating neurodegenerative changes in early cognitive decline. Further research with larger cohorts and longer follow-up periods is needed to confirm these findings and understand the mechanisms involved.

Experimental GerontologyVol. 202
Shanghai Stomatological Hospital (CN), Community Health Center (US), Tongji Hospital (CN), Yangpu Hospital of Tongji University (CN)
Good health and well-being
Openalex Percentile: Top 14%
Alzheimer's disease research and treatments
2.33
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