Statin is associated with higher cortical thickness in early Alzheimer's disease
Statin use is associated with greater cortical thickness in older adults, particularly in those with MCI. These findings suggest that statins may have neuroprotective effects, potentially mitigating neurodegenerative changes in early cognitive decline. Further research with larger cohorts and longer follow-up periods is needed to confirm these findings and understand the mechanisms involved.
Authors
- Yu‐Ming Kong
- Yufei Zheng (ORCID: https://orcid.org/0000-0002-3800-7676)
- Huiying Gu
Institutions
- Shanghai Stomatological Hospital (CN)
- Community Health Center (US)
- Tongji Hospital (CN)
- Yangpu Hospital of Tongji University (CN)
Publication Details
- Journal
- Experimental Gerontology
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1016/j.exger.2025.112698
- Citations
- 2
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.33