On the use of sham transcutaneous spinal cord stimulation in spinal cord injury clinical trials
Kramer et al. examine the reasons put forth by investigators for excluding a sham condition in trials of neuromodulation therapies for individuals with spinal cord injury. They conclude that current dogma does not justify this design, and emphasize the need for future trials to include appropriate controls.
Authors
- Tania Lam (ORCID: https://orcid.org/0000-0002-5782-2537)
- Judy Illes (ORCID: https://orcid.org/0000-0002-4791-8084)
- John L. K. Kramer (ORCID: https://orcid.org/0000-0001-7722-131X)
- Fábio Rossi (ORCID: https://orcid.org/0000-0002-0368-2620)
Institutions
- Vancouver Coastal Health (CA)
- University of British Columbia (CA)
- International Collaboration On Repair Discoveries (CA)
- NeuroDevNet (CA)
- Vancouver Coastal Health Research Institute (CA)
Publication Details
- Journal
- Brain
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1093/brain/awaf040
- Citations
- 2
- Primary Topic
- Pain Management and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.38
Funders
- Government of Canada