Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH–tanycyte unit function of polycystic ovary syndrome
EA exerts therapeutic effects on PCOS by targeting hypothalamic GnRH-tanycyte unit, with Itgb1 identified as a key factor. MA primarily functions through neurotransmitter regulation. These findings highlight potential hypothalamic targets and provide new insights into the distinct mechanisms of EA and MA.
Authors
- Rui Huang (ORCID: https://orcid.org/0000-0001-5367-8171)
- Yi Feng (ORCID: https://orcid.org/0000-0002-7156-6023)
- Wenhao Gao
- Wenhan Lu (ORCID: https://orcid.org/0000-0003-3890-5553)
- Jiajia Li (ORCID: https://orcid.org/0000-0003-0577-0963)
- Xiaoyu Tong (ORCID: https://orcid.org/0000-0002-1343-6335)
- Wei Hu (ORCID: https://orcid.org/0000-0002-9107-8027)
- Yu Wang (ORCID: https://orcid.org/0000-0001-8697-2940)
- Yicong Wang (ORCID: https://orcid.org/0000-0001-9102-4363)
- Yuning Chen (ORCID: https://orcid.org/0009-0007-4010-2756)
Institutions
- Fudan University (CN)
- Eye & ENT Hospital of Fudan University (CN)
- Shanghai Research Center for Acupuncture and Meridians (CN)
- China Association of Acupuncture-Moxibustion (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1186/s13020-025-01068-3
- Citations
- 6
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 14.29
Funders
- National Natural Science Foundation of China