Investigating Brain Structure and Functional Alterations in the Transition from Acute to Chronic Neck Pain: A Resting-State fMRI Study

Our findings indicate that dysfunction and structural changes in the limbic system and prefrontal cortex may play a pivotal role in the progression from acute to chronic neck pain. These insights provide a significant new direction for understanding the central mechanisms underlying pain chronicity.

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Publication Details

Journal
Journal of Pain Research
Published
2025-02-01
DOI
https://doi.org/10.2147/jpr.s500924
Citations
4
Primary Topic
Musculoskeletal pain and rehabilitation
Type
article
Field-Weighted Citation Impact
5.58

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article

Investigating Brain Structure and Functional Alterations in the Transition from Acute to Chronic Neck Pain: A Resting-State fMRI Study

Laixi Ji, Mengjie Cui, Jing Zhang, Haijun Wang et al.
4 citations
Journal of Pain Research
Musculoskeletal pain and rehabilitation
5.58
article

Investigating Brain Structure and Functional Alterations in the Transition from Acute to Chronic Neck Pain: A Resting-State fMRI Study

Laixi Ji, Mengjie Cui, Jing Zhang, Haijun Wang, Zhen Gao, Cheng Xu
article en
4 citations

Abstract

Our findings indicate that dysfunction and structural changes in the limbic system and prefrontal cortex may play a pivotal role in the progression from acute to chronic neck pain. These insights provide a significant new direction for understanding the central mechanisms underlying pain chronicity.

Journal of Pain ResearchVol. Volume 18
Shanxi Medical University (CN), Shanxi University of Traditional Chinese Medicine (CN), Shanxi Provincial People’s Hospital (CN)
Shanxi University
Good health and well-being
Openalex Percentile: Top 5%
Musculoskeletal pain and rehabilitation
5.58
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Investigating Brain Structure and Functional Alterations in the Transition from Acute to Chronic Neck Pain: A Resting-State fMRI Study — Laixi Ji, Mengjie Cui, et al. · Journal of Pain Research (2025) | TGRS Research Map | TGRS