The Impact of Immune‐Related Adverse Event Severity on Prognosis in Elderly Patients With Nonsmall‐Cell Lung Cancer in First‐Line Immune Checkpoint Inhibitor Treatment
Severe irAEs demonstrated different outcomes in elderly and nonelderly patients. Contrastingly, mild irAEs were associated with a favorable prognosis in elderly patients, emphasizing the need for appropriate patient selection, early intervention for irAEs and new tools to accurately predict irAE severity in elderly patients.
Authors
- Yasuhiro Gon
- Yu Mizuno (ORCID: https://orcid.org/0000-0002-7994-5300)
- Ippei Miyamoto (ORCID: https://orcid.org/0000-0003-2325-5498)
- Yoshiko Nakagawa (ORCID: https://orcid.org/0000-0003-4807-3797)
- Ryota Nakayama
- Ryo Kusahana
- Masayuki Nomoto
- Tetsuo Shimizu (ORCID: https://orcid.org/0000-0003-3405-9652)
- Mizuki Hanamura
Institutions
- Nihon University (JP)
Publication Details
- Journal
- Thoracic Cancer
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1111/1759-7714.70006
- Citations
- 4
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 4.18